Androgenic steroids meaning
Second, these steroids are androgenic or virilizing , meaning in particular that they affect the development and maintenance of masculine characteristics. For example, a number of compounds have been found in female breasts to have been androgenic because of its effects on the development of breast bone formation and the secretion of breast hormone (17). The effects of the synthetic anandamide (17) and 2-alpha-androstanediol (17), in particular, have been suggested to have a feminizing effect on the brain (18), whereas this effect has been associated with estrogen in rats (19, 20) and with progesterone in man (21-23), androgenic steroids bodybuilding. Both synthetic anandamide and naltrexone (22) are structurally related to endogenous ligands of androgen receptors (24). Both anandamide and naltrexone also act on androgen receptor-cAMP (25, 26), which enhances the formation of male sex hormones at synaptosomal membranes (27), androgenic steroids muscle mass. Thus, these steroids may act to reduce female breast development (27), and by this mechanism, decrease testosterone levels, androgenic steroids bile acids. Additionally, these compounds can prevent or reduce the production of other androgens by the adrenal gland (28), and may also reduce androgen production by the ovary and preovulatory epithelial cells (29, 30). The estrogen and progesterone-activating compounds of these steroids may also affect male sexual development to a greater extent than the androgens, thereby preventing and reversing the pubertal changes (31, 32); however, it is not known whether the specific effects of these synthetic steroids (i.e., the effects of anandamide and naltrexone on the production of male sex hormone) are the source of the feminizing effects on the development of the male breast development (6)—that is, whether they are acting directly on the hypothalamus, or whether these synthetic steroids affect other androgen receptors on the X chromosome (or a subset of them) to also promote breast development (5, 18). Because the mechanisms underlying the relationship between the steroid hormones and breast development and the effects of these particular steroids on the development of the male breast have not been fully elucidated, it is unclear what role these steroids may play in the development of the male breast, androgenic steroids meaning.
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